| Summary: | Iron(III) is well-known to play a vital role in a variety of metabolic processes in almost all living systems, including the human body. However, the excess or deficiency of Fe<sup>3+</sup> from the normal permissible limit can cause serious health problems. Therefore, novel analytical methods are developed for the simple, direct, and cost-effective monitoring of Fe<sup>3+</sup> concentration in various environmental and biological samples. Because of the high selectivity and sensitivity, fast response time, and simplicity, the fluorescent-based molecular probes have been developed extensively in the past few decades to detect Fe<sup>3+</sup>. This review was narrated to summarize the Fe<sup>3+</sup>-selective fluorescent probes that show fluorescence enhancement (turn-on) and ratiometric response. The Fe<sup>3+</sup> sensing ability, mechanisms along with the analytical novelties of recently reported 77 fluorescent probes are discussed.
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