RNA-sequencing in non-small cell lung cancer shows gene downregulation of therapeutic targets in tumor tissue compared to non-malignant lung tissue

RNA-sequencing in non-small cell lung cancer shows gene downregulation of therapeutic targets in tumor tissue compared to non-malignant lung tissue

Abstract Background Gene expression of specific therapeutic targets in non-malignant lung tissue might play an important role in optimizing targeted therapies. This study aims to identify different expression patterns of fifteen genes important for targeted therapy in non-small cell lung cancer (NSC...

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Bibliographic Details
Main Authors: Kobe Reynders, Els Wauters, Matthieu Moisse, Herbert Decaluwé, Paul De Leyn, Stéphanie Peeters, Maarten Lambrecht, Kristiaan Nackaerts, Christophe Dooms, Wim Janssens, Johan Vansteenkiste, Diether Lambrechts, Dirk De Ruysscher
Format: Article
Language:English
Published: BMC 2018-07-01
Series:Radiation Oncology
Subjects:
Targeted treatment
NSCLC
PD-L1
RNA-sequencing
Online Access:http://link.springer.com/article/10.1186/s13014-018-1075-1

Internet

http://link.springer.com/article/10.1186/s13014-018-1075-1

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