Transcriptional profiling of intervertebral disc in a post‐traumatic early degeneration organ culture model

Transcriptional profiling of intervertebral disc in a post‐traumatic early degeneration organ culture model

Abstract Introduction The goal of this study is to characterize transcriptome changes and gene regulation networks in an organ culture system that mimics early post‐traumatic intervertebral disc (IVD) degeneration. Methods To mimic a traumatic insult, bovine caudal IVDs underwent one strike loading....

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Bibliographic Details
Main Authors: Shangbin Cui, Zhiyu Zhou, Xu Chen, Fuxin Wei, R. Geoff Richards, Mauro Alini, Sibylle Grad, Zhen Li
Format: Article
Language:English
Published: Wiley 2021-09-01
Series:JOR Spine
Subjects:
biomarker
immunofluorescence
intervertebral disc
organ culture
RNA sequencing
traumatic
Online Access:https://doi.org/10.1002/jsp2.1146

Internet

https://doi.org/10.1002/jsp2.1146

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