Prevalence, Patterns and Predictors of Chronic Complications of Diabetes Mellitus at a Large Referral Hospital in Ethiopia: A Prospective Observational Study

• Main Authors: Sheleme T, Mamo G, Melaku T, Sahilu T
• Format: Article
• Language: English
• Published: Dove Medical Press 2020-12-01
• Series: Diabetes, Metabolic Syndrome and Obesity : Targets and Therapy
• Subjects: diabetes; chronic complications; mettu karl referral hospital; ethiopia
• Online Access: https://www.dovepress.com/prevalence-patterns-and-predictors-of-chronic-complications-of-diabete-peer-reviewed-article-DMSO

Tadesse Sheleme,1 Girma Mamo,2 Tsegaye Melaku,2 Tamiru Sahilu3 1Department of Pharmacy, College of Health Science, Mettu University, Mettu, Ethiopia; 2School of Pharmacy, Institute of Health, Jimma University, Jimma, Ethiopia; 3Department of Pharmacy, College of Health Science, Assosa University, Assosa, EthiopiaCorrespondence: Tadesse ShelemeDepartment of Pharmacy, College of Health Science, Mettu University, P.O. Box: 318, Mettu, EthiopiaTel [phone]Email [e-mail]: Diabetes mellitus complications are responsible for increased disability, morbidity, and mortality. This study aimed to assess prevalence, patterns, and predictors of chronic complications of diabetes among people with diabetes.Patients and Methods: The study was conducted using a prospective observational study design which was done on people with diabetes attending the ambulatory clinic of Mettu Karl Referral Hospital. The data were collected using a consecutive type of sampling technique from April 15 to August 9, 2019. The data were entered into Epidata manager version 4.4.2. Logistic regression analysis was done to identify predictors of chronic complications of diabetes.Results: A total of 330 participants were included in this study. The mean age of participants was 49.9± 14.2, and 156 (47.3%) were 41 to 60 years old. About 127 (38.5%) had one or more chronic complications. The predictors of chronic diabetes complications were resident in urban areas [AOR: 1.94; 95% CI: (1.17, 3.20); p = 0.010], duration of diabetes 10 years [AOR: 2.05, 95% CI: (1.21, 3.47); p = 0.007], hypertension [AOR: 4.19; 95% CI: (2.54, 6.91); p < 0.001] and poor glycemic control [AOR: 2.82; 95% CI: (1.53, 5.21); p = 0.001].Conclusion: Almost two-fifth of the study participants had chronic complications of diabetes. Residents in urban areas, longer duration of diabetes, hypertension and poor glycemic control were predictors of chronic diabetes complications. It is important to achieve good glycemic control and manage comorbid diseases like hypertension to minimize the risk of chronic diabetes complications.Keywords: diabetes mellitus, chronic complications, Mettu Karl Referral Hospital, Ethiopia