Genetic Model to Study the Co-Morbid Phenotypes of Increased Alcohol Intake and Prior Stress-Induced Enhanced Fear Memory

Genetic Model to Study the Co-Morbid Phenotypes of Increased Alcohol Intake and Prior Stress-Induced Enhanced Fear Memory

Posttraumatic Stress Disorder (PTSD) is a complex illness, frequently co-morbid with depression, caused by both genetics, and the environment. Alcohol Use Disorder (AUD), which also co-occurs with depression, is often co-morbid with PTSD. To date, very few genes have been identified for PTSD and eve...

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Bibliographic Details
Main Authors: Patrick Henry Lim, Guang Shi, Tengfei Wang, Sophia T. Jenz, Megan K. Mulligan, Eva E. Redei, Hao Chen
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-11-01
Series:Frontiers in Genetics
Subjects:
alcohol self-administration
genetic model of depression
contextual fear conditioning
corticosterone
glucocorticoid receptor
alcohol use disorder
Online Access:https://www.frontiersin.org/article/10.3389/fgene.2018.00566/full

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https://www.frontiersin.org/article/10.3389/fgene.2018.00566/full

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