Airway Mucus and Asthma: The Role of MUC5AC and MUC5B

Asthma is characterized by mucus abnormalities. Airway epithelial hyperplasia and metaplasia result in changes in stored and secreted mucin and the production of a pathologic mucus gel. Mucus transport is impaired, culminating in mucus plugging and airway obstruction—a major cause of morbidity in as...

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Bibliographic Details
Main Authors: Luke R. Bonser, David J. Erle
Format: Article
Language:English
Published: MDPI AG 2017-11-01
Series:Journal of Clinical Medicine
Subjects:
Online Access:https://www.mdpi.com/2077-0383/6/12/112