Effects of carvedilol on structural and functional outcomes and plasma biomarkers in the mouse transverse aortic constriction heart failure model

Effects of carvedilol on structural and functional outcomes and plasma biomarkers in the mouse transverse aortic constriction heart failure model

Introduction: Despite the widespread use of the mouse transverse aortic constriction heart failure model, there are no reports on the characterization of the standard-of-care agent carvedilol in this model. Methods: Left ventricular pressure overload was produced in mice by transverse aortic constri...

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Bibliographic Details
Main Authors: Caryn Hampton, Raymond Rosa, Daphne Szeto, Gail Forrest, Barry Campbell, Richard Kennan, Shubing Wang, Chin-Hu Huang, Loise Gichuru, Xiaoli Ping, Xiaolan Shen, Kersten Small, Jeffrey Madwed, Joseph J Lynch
Format: Article
Language:English
Published: SAGE Publishing 2017-03-01
Series:SAGE Open Medicine
Online Access:https://doi.org/10.1177/2050312117700057

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https://doi.org/10.1177/2050312117700057

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