Obsessive-Compulsive Symptoms, Polygenic Risk Score, and Thalamic Development in Children From the Brazilian High-Risk Cohort for Mental Conditions (BHRCS)

Background: Thalamic volume measures have been linked to obsessive-compulsive disorder (OCD) in children and adolescents. However, it is unclear if alterations in thalamic volumes occur before or after symptom onset and if there is a relation to the presence of sub-clinical obsessive-compulsive symp...

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Main Authors: Ana Beatriz Ravagnani Salto, Marcos L. Santoro, Marcelo Q. Hoexter, Andrea Parolin Jackowski, Pedro M. Pan, Maria Conceição Rosário, Sintia I. Belangero, Pedro Gomes Alvarenga, Victoria Fogaça Doretto, Afonso Mazine Tiago Fumo, Marcelo C. Batistuzzo, Pedro Macul Ferreira de Barros, Kiara R. Timpano, Vanessa K. Ota, Luis Augusto Rohde, Euripedes Constantino Miguel, James F. Leckman, André Zugman
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-06-01
Series:Frontiers in Psychiatry
Subjects:
MRI
Online Access:https://www.frontiersin.org/articles/10.3389/fpsyt.2021.673595/full