Abnormal blood–brain barrier permeability in normal appearing white matter in multiple sclerosis investigated by MRI

Abnormal blood–brain barrier permeability in normal appearing white matter in multiple sclerosis investigated by MRI

Objectives: To investigate whether blood–brain barrier (BBB) permeability is disrupted in normal appearing white matter in MS patients, when compared to healthy controls and whether it is correlated with MS clinical characteristics. Methods: Dynamic contrast-enhanced MRI was used to measure BBB perm...

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Bibliographic Details
Main Authors: S.P. Cramer, H. Simonsen, J.L. Frederiksen, E. Rostrup, H.B.W. Larsson
Format: Article
Language:English
Published: Elsevier 2014-01-01
Series:NeuroImage: Clinical
Subjects:
MRI
DCE MRI
Perfusion MRI
Blood–brain barrier
Disease modifying therapy
Multiple sclerosis
Online Access:http://www.sciencedirect.com/science/article/pii/S2213158213001605

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http://www.sciencedirect.com/science/article/pii/S2213158213001605

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