Sepsis-Associated Encephalopathy: The Blood–Brain Barrier and the Sphingolipid Rheostat

Sepsis is not only a significant cause of mortality worldwide but has particularly devastating effects on the central nervous system of survivors. It is therefore crucial to understand the molecular structure, physiology, and events involved in the pathogenesis of sepsis-associated encephalopathy, s...

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Bibliographic Details
Main Authors: Stephen J. Kuperberg, Raj Wadgaonkar
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-06-01
Series:Frontiers in Immunology
Subjects:
Online Access:http://journal.frontiersin.org/article/10.3389/fimmu.2017.00597/full