Peripheral Nerve Regeneration through Hydrogel-Enriched Chitosan Conduits Containing Engineered Schwann Cells for Drug Delivery
Critical length nerve defects in the rat sciatic nerve model were reconstructed with chitosan nerve guides filled with Schwann cells (SCs) containing hydrogel. The transplanted SCs were naive or had been genetically modified to overexpress neurotrophic factors, thus providing a cellular neurotrophic...
Main Authors: | , , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
SAGE Publishing
2016-01-01
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Series: | Cell Transplantation |
Online Access: | https://doi.org/10.3727/096368915X688010 |