Fine-mapping of the human leukocyte antigen locus as a risk factor for Alzheimer disease: A case-control study.

Fine-mapping of the human leukocyte antigen locus as a risk factor for Alzheimer disease: A case-control study.

<h4>Background</h4>Alzheimer disease (AD) is a progressive disorder that affects cognitive function. There is increasing support for the role of neuroinflammation and aberrant immune regulation in the pathophysiology of AD. The immunoregulatory human leukocyte antigen (HLA) complex has b...

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Main Authors: Natasha Z R Steele, Jessie S Carr, Luke W Bonham, Ethan G Geier, Vincent Damotte, Zachary A Miller, Rahul S Desikan, Kevin L Boehme, Shubhabrata Mukherjee, Paul K Crane, John S K Kauwe, Joel H Kramer, Bruce L Miller, Giovanni Coppola, Jill A Hollenbach, Yadong Huang, Jennifer S Yokoyama
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-03-01
Series:PLoS Medicine
Online Access:https://doi.org/10.1371/journal.pmed.1002272

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https://doi.org/10.1371/journal.pmed.1002272

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