Multiple aspects of male germ cell development and interactions with Sertoli cells require inositol hexakisphosphate kinase-1

Multiple aspects of male germ cell development and interactions with Sertoli cells require inositol hexakisphosphate kinase-1

Abstract Inositol hexakisphosphate kinase-1 (IP6K1) is required for male fertility, but the underlying mechanisms have been elusive. Here, we report that IP6K1 is required for multiple aspects of male germ cell development. This development requires selective interactions between germ cells and Sert...

Full description

Bibliographic Details
Main Authors: Chenglai Fu, Tomas Rojas, Alfred C. Chin, Weiwei Cheng, Isaac A. Bernstein, Lauren K. Albacarys, William W. Wright, Solomon H. Snyder
Format: Article
Language:English
Published: Nature Publishing Group 2018-05-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-018-25468-8

Internet

https://doi.org/10.1038/s41598-018-25468-8

Similar Items