Hydrogen bond based smart polymer for highly selective and tunable capture of multiply phosphorylated peptides

Capture of low-abundance multiply phosphorylated peptides (MPPs) is difficult due to limitation of enrichment materials and their interactions with phosphates. Here the authors show, a smart polymer driven by specific but tunable hydrogen bonding interactions can differentially complex with MPPs, si...

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Bibliographic Details
Main Authors: Guangyan Qing, Qi Lu, Xiuling Li, Jing Liu, Mingliang Ye, Xinmiao Liang, Taolei Sun
Format: Article
Language:English
Published: Nature Publishing Group 2017-09-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-017-00464-0