Role of probiotics in the treatment and prevention of oral malodor/halitosis: A systematic review

Oral malodor is a condition which impedes people's social life and self-esteem. With more widespread acceptance of the potential for probiotic intervention providing health benefits for nonintestinal body sites, application of it on alternative target tissues has increased, to obtain more speci...

Full description

Bibliographic Details
Main Authors: Pragati Ishwar Shringeri, Nusrath Fareed, Hemant Battur, Sanjeev Khanagar
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2019-01-01
Series:Journal of Indian Association of Public Health Dentistry
Subjects:
Online Access:http://www.jiaphd.org/article.asp?issn=2319-5932;year=2019;volume=17;issue=2;spage=90;epage=96;aulast=Shringeri
id doaj-f7e612abc25b4de3b19dad9772690a8a
record_format Article
spelling doaj-f7e612abc25b4de3b19dad9772690a8a2020-11-25T00:12:29ZengWolters Kluwer Medknow PublicationsJournal of Indian Association of Public Health Dentistry2319-59322350-04842019-01-01172909610.4103/jiaphd.jiaphd_171_18Role of probiotics in the treatment and prevention of oral malodor/halitosis: A systematic reviewPragati Ishwar ShringeriNusrath FareedHemant BatturSanjeev KhanagarOral malodor is a condition which impedes people's social life and self-esteem. With more widespread acceptance of the potential for probiotic intervention providing health benefits for nonintestinal body sites, application of it on alternative target tissues has increased, to obtain more specific and enduring benefits. From the periodontal perspective, several studies have revealed the role of probiotic in the reduction of gingival inflammation. However, the studies of stronger evidence pertaining to the role of probiotics in the treatment and prevention of halitosis is limited. The aim of this study was to determine the role of probiotic strains in the treatment and prevention of oral malodor. Records were searched from various databases such as PubMed/Medline, Cochrane, and EMBASE. Articles published over the past 11 years were identified using the key search terms. A total of 178 records were identified by title/abstracts/full-text articles and were retrieved. After thorough assessment, 11 manuscripts were included in qualitative synthesis in this systematic review. Analysis of studies revealed 666 participants, aged 4–76 years, and about 20 probiotic strains were assigned to the test groups and control groups with a varying follow-up period. The effect size for randomized control trials ranged from 0.08 to 0.7 which suggests low-to-moderate practical significance. The results of this systematic review confirm that more studies are necessary to evaluate the efficacy of probiotics with correct methodological design, in broader population samples, and over longer periods.http://www.jiaphd.org/article.asp?issn=2319-5932;year=2019;volume=17;issue=2;spage=90;epage=96;aulast=ShringeriHalitosisoral malodorprobioticsvolatile sulfur compound
collection DOAJ
language English
format Article
sources DOAJ
author Pragati Ishwar Shringeri
Nusrath Fareed
Hemant Battur
Sanjeev Khanagar
spellingShingle Pragati Ishwar Shringeri
Nusrath Fareed
Hemant Battur
Sanjeev Khanagar
Role of probiotics in the treatment and prevention of oral malodor/halitosis: A systematic review
Journal of Indian Association of Public Health Dentistry
Halitosis
oral malodor
probiotics
volatile sulfur compound
author_facet Pragati Ishwar Shringeri
Nusrath Fareed
Hemant Battur
Sanjeev Khanagar
author_sort Pragati Ishwar Shringeri
title Role of probiotics in the treatment and prevention of oral malodor/halitosis: A systematic review
title_short Role of probiotics in the treatment and prevention of oral malodor/halitosis: A systematic review
title_full Role of probiotics in the treatment and prevention of oral malodor/halitosis: A systematic review
title_fullStr Role of probiotics in the treatment and prevention of oral malodor/halitosis: A systematic review
title_full_unstemmed Role of probiotics in the treatment and prevention of oral malodor/halitosis: A systematic review
title_sort role of probiotics in the treatment and prevention of oral malodor/halitosis: a systematic review
publisher Wolters Kluwer Medknow Publications
series Journal of Indian Association of Public Health Dentistry
issn 2319-5932
2350-0484
publishDate 2019-01-01
description Oral malodor is a condition which impedes people's social life and self-esteem. With more widespread acceptance of the potential for probiotic intervention providing health benefits for nonintestinal body sites, application of it on alternative target tissues has increased, to obtain more specific and enduring benefits. From the periodontal perspective, several studies have revealed the role of probiotic in the reduction of gingival inflammation. However, the studies of stronger evidence pertaining to the role of probiotics in the treatment and prevention of halitosis is limited. The aim of this study was to determine the role of probiotic strains in the treatment and prevention of oral malodor. Records were searched from various databases such as PubMed/Medline, Cochrane, and EMBASE. Articles published over the past 11 years were identified using the key search terms. A total of 178 records were identified by title/abstracts/full-text articles and were retrieved. After thorough assessment, 11 manuscripts were included in qualitative synthesis in this systematic review. Analysis of studies revealed 666 participants, aged 4–76 years, and about 20 probiotic strains were assigned to the test groups and control groups with a varying follow-up period. The effect size for randomized control trials ranged from 0.08 to 0.7 which suggests low-to-moderate practical significance. The results of this systematic review confirm that more studies are necessary to evaluate the efficacy of probiotics with correct methodological design, in broader population samples, and over longer periods.
topic Halitosis
oral malodor
probiotics
volatile sulfur compound
url http://www.jiaphd.org/article.asp?issn=2319-5932;year=2019;volume=17;issue=2;spage=90;epage=96;aulast=Shringeri
work_keys_str_mv AT pragatiishwarshringeri roleofprobioticsinthetreatmentandpreventionoforalmalodorhalitosisasystematicreview
AT nusrathfareed roleofprobioticsinthetreatmentandpreventionoforalmalodorhalitosisasystematicreview
AT hemantbattur roleofprobioticsinthetreatmentandpreventionoforalmalodorhalitosisasystematicreview
AT sanjeevkhanagar roleofprobioticsinthetreatmentandpreventionoforalmalodorhalitosisasystematicreview
_version_ 1725399372924977152