Zoledronic acid sensitizes renal cell carcinoma cells to radiation by downregulating STAT1.

Zoledronic acid (ZOL), a third-generation bisphosphonate that strongly inhibits osteoclast activity, is widely used for the treatment of bone metastasis from a variety of malignancies, including renal cell carcinoma (RCC). We previously reported that zoledronic acid (ZOL) clinically potentiates anti...

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Bibliographic Details
Main Authors: Toshiki Kijima, Fumitaka Koga, Yasuhisa Fujii, Soichiro Yoshida, Manabu Tatokoro, Kazunori Kihara
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3669422?pdf=render