Neuroprotective Effects of Mitochondria-Targeted Plastoquinone and Thymoquinone in a Rat Model of Brain Ischemia/Reperfusion Injury
We explored the neuroprotective properties of natural plant-derived antioxidants plastoquinone and thymoquinone (2-demethylplastoquinone derivative) modified to be specifically accumulated in mitochondria. The modification was performed through chemical conjugation of the quinones with penetrating c...
Main Authors: | Denis N. Silachev, Egor Y. Plotnikov, Ljubava D. Zorova, Irina B. Pevzner, Natalia V. Sumbatyan, Galina A. Korshunova, Mikhail V. Gulyaev, Yury A. Pirogov, Vladimir P. Skulachev, Dmitry B. Zorov |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2015-08-01
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Series: | Molecules |
Subjects: | |
Online Access: | http://www.mdpi.com/1420-3049/20/8/14487 |
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