Multi-targeted mechanisms underlying the endothelial protective effects of the diabetic-safe sweetener erythritol.

Diabetes is characterized by hyperglycemia and development of vascular pathology. Endothelial cell dysfunction is a starting point for pathogenesis of vascular complications in diabetes. We previously showed the polyol erythritol to be a hydroxyl radical scavenger preventing endothelial cell dysfunc...

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Bibliographic Details
Main Authors: Daniëlle M P H J Boesten, Alvin Berger, Peter de Cock, Hua Dong, Bruce D Hammock, Gertjan J M den Hartog, Aalt Bast
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3673924?pdf=render