Carcinoma initiation via RB tumor suppressor inactivation: a versatile approach to epithelial subtype-dependent cancer initiation in diverse tissues.

Carcinoma initiation via RB tumor suppressor inactivation: a versatile approach to epithelial subtype-dependent cancer initiation in diverse tissues.

Carcinomas arise in a complex microenvironment consisting of multiple distinct epithelial lineages surrounded by a variety of stromal cell types. Understanding cancer etiologies requires evaluating the relationship among cell types during disease initiation and through progression. Genetically engin...

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Bibliographic Details
Main Authors: Yurong Song, Debra Gilbert, T Norene O'Sullivan, Chunyu Yang, Wenqi Pan, Alisan Fathalizadeh, Lucy Lu, Diana C Haines, Philip L Martin, Terry Van Dyke
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24312475/?tool=EBI

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https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24312475/?tool=EBI

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