Effects of New NSAID-CAI Hybrid Compounds in Inflammation and Lung Fibrosis

Effects of New NSAID-CAI Hybrid Compounds in Inflammation and Lung Fibrosis

Pulmonary fibrosis is a severe lung disease with progressive worsening of dyspnea, characterized by chronic inflammation and remodeling of lung parenchyma. Carbonic anhydrases are a family of zinc-metallo-enzymes that catalyze the reversible interconversion of carbon-dioxide and water to bicarbonate...

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Bibliographic Details
Main Authors: Laura Lucarini, Mariaconcetta Durante, Silvia Sgambellone, Cecilia Lanzi, Elisabetta Bigagli, Ozlem Akgul, Emanuela Masini, Claudiu T. Supuran, Fabrizio Carta
Format: Article
Language:English
Published: MDPI AG 2020-09-01
Series:Biomolecules
Subjects:
NSAIDs
CAI
inflammation
pulmonary fibrosis
COX-1
COX-2
Online Access:https://www.mdpi.com/2218-273X/10/9/1307

Internet

https://www.mdpi.com/2218-273X/10/9/1307

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