Novel siRNA delivery system to target podocytes in vivo.

Novel siRNA delivery system to target podocytes in vivo.

Podocytes are injured in several glomerular diseases. To alter gene expression specifically in podocytes in vivo, we took advantage of their active endocytotic machinery and developed a method for the targeted delivery of small interfering ribonucleic acids (siRNA). We generated an anti-mouse podocy...

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Bibliographic Details
Main Authors: Peter V Hauser, Jeffrey W Pippin, Cora Kaiser, Ronald D Krofft, Paul T Brinkkoetter, Kelly L Hudkins, Dontscho Kerjaschki, Jochen Reiser, Charles E Alpers, Stuart J Shankland
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-03-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2830889?pdf=render

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http://europepmc.org/articles/PMC2830889?pdf=render

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