The Role of Cystinosin in the Intermediary Thiol Metabolism and Redox Homeostasis in Kidney Proximal Tubular Cells

Cystinosin is a lysosomal transmembrane protein which facilitates transport of the disulphide amino acid cystine (CySS) from the lysosomes of the cell. This protein is encoded by the CTNS gene which is defective in the lysosomal storage disorder, cystinosis. Because of the apparent involvement of cy...

Full description

Bibliographic Details
Main Authors: Rodolfo Sumayao, Philip Newsholme, Tara McMorrow
Format: Article
Published: MDPI AG 2018-12-01
Online Access: