The transcriptional regulator CBP has defined spatial associations within interphase nuclei.

It is becoming increasingly clear that nuclear macromolecules and macromolecular complexes are compartmentalized through binding interactions into an apparent three-dimensionally ordered structure. This ordering, however, does not appear to be deterministic to the extent that chromatin and nonchroma...

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Bibliographic Details
Main Authors: Kirk J McManus, David A Stephens, Niall M Adams, Suhail A Islam, Paul S Freemont, Michael J Hendzel
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2006-10-01
Series:PLoS Computational Biology
Online Access:https://doi.org/10.1371/journal.pcbi.0020139