Primary non-Hodgkins lymphoma of eye and adnexa. Effect of method of treatment for prognosis

• Main Authors: E. E. Grishina, E. S. Guzenko
• Format: Article
• Language: Russian
• Published: Ophthalmology Publishing Group 2014-07-01
• Series: Oftalʹmologiâ
• Subjects: eye non-Hodgkins lymphoma; prognosis
• Online Access: http://www.ophthalmojournal.com/index.php/opht/article/view/52

<p><strong>Purpose:</strong> To identify predictors of NHL of the vision associated with treatment choice for prognosis of primary non-Hodgkin’s lymphoma eye and adnexa.</p><p><br /><strong>Methods:</strong> A retrospective and prospective study characteristics of the disease in 94 patients with primary lymphoma of the vision. Orbital lymphoma diagnosed in 35 patients (36 %), conjunctival — in 48 patients (52 %), the least damage observed age — 11 patients (12 %). Among the various types of malignant lymphomas morphologic immunological dominated B-cell lymphoma or marginal zone MALT-lymphoma, which were diagnosed in 70 (75 %). Patients were treated with radiation, chemotherapy and combined chemoradiotherapy.</p><p><br /><strong>Results:</strong> During the follow-up period of 1 year to 26 years (median follow-up 5 years) of the 94 patients the primary lymphoma of the vision in 22 cases (23 %) relapses occurred in a period of 6 months to 10 years (median 2 years). In analyzing the data we found that the 5‑year disease-free survival with radiation therapy, chemotherapy, and combination therapy is the same and is equal to — 70 %.</p><p><br /><strong>Conclusion:</strong> The treatment and monitoring of patients with primary non-Hodgkin’s lymphoma eye and adnexa should be implemented jointly ophthalmologist and oncology. The choice of treatment, with adequate treatment is prescribed, can not be associated with the weather and can not be a predictor of the primary non-Hodgkin’s lymphoma eye and adnexa.</p>