Synthesis and Bioevaluation of 5-Fluorouracil Derivatives

A series of six novel 5-fluorouracil derivatives 1-6 were synthesized and theirstructures confirmed by 1H- and 13C-NMR, MS and elemental analysis. The preliminary invitro antitumor activities against B16, K562 and CHO cells and the in vivo inhibitions ofliver cancer H22 demonstrated that some of the...

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Bibliographic Details
Main Authors: Chao-Jie Wang, Wen-Yuan Gao, Jin Zhao, Song-Qiang Xie, Gang-Jun Du, Zhi-Yong Tian
Format: Article
Published: MDPI AG 2007-11-01
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