Biomechanical-Based Protocol for in vitro Study of Cartilage Response to Cyclic Loading: A Proof-of-Concept in Knee Osteoarthritis

Osteoarthritis (OA) is an evolving disease and a major cause of pain and impaired mobility. A deeper understanding of cartilage metabolism in response to loading is critical to achieve greater insight into OA mechanisms. While physiological joint loading helps maintain cartilage integrity, reduced o...

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Bibliographic Details
Main Authors: Paolo Caravaggi, Elisa Assirelli, Andrea Ensini, Maurizio Ortolani, Erminia Mariani, Alberto Leardini, Simona Neri, Claudio Belvedere
Format: Article
Published: Frontiers Media S.A. 2021-05-01
Series:Frontiers in Bioengineering and Biotechnology
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