Fate of Embryonic Stem Cells Transplanted into the Deafened Mammalian Cochlea

Spiral ganglion neurons (SGNs), the primary afferent neurons of the cochlea, degenerate following a sensorineural hearing loss (SNHL) due to lack of trophic support normally received from hair cells. Cell transplantation is emerging as a potential strategy for inner ear rehabilitation, as injected c...

Full description

Bibliographic Details
Main Authors: B. Coleman, J. Hardman, A. Coco, S. Epp, M. De Silva, J. Crook, R. Shepherd
Format: Article
Language:English
Published: SAGE Publishing 2006-05-01
Series:Cell Transplantation
Online Access:https://doi.org/10.3727/000000006783981819