Norcembranoidal Diterpenes from a Formosan Soft Coral Sinularia sp.

Norcembranoidal Diterpenes from a Formosan Soft Coral Sinularia sp.

Two norcembranoidal diterpenes, 5-episinuleptolide acetate (1) and scabrolide D (2), were isolated from a Formosan octocoral identified as Sinularia sp. The structures of norcembranoids 1 and 2 were established by spectroscopic methods and by comparison of the spectral data with those of known analo...

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Main Authors: Yueh-Hsiung Kuo, Ping-Jyun Sung, Ching-Feng Weng, Chia-Hung Lee, Show-Ying Yang, Yung-Chi Kuo, Wen-Hung Twan, Mei-Chin Lu, Jui-Hsin Su, Wei-Hsuan Yen, Li-Chung Hu
Format: Article
Language:English
Published: MDPI AG 2012-11-01
Series:Molecules
Subjects:
Sinularia
norcembranoidal diterpene
cytotoxicity
Online Access:http://www.mdpi.com/1420-3049/17/12/14058
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spelling doaj-fa44b77b24104e4f8d3aebde6b23d80e2020-11-24T22:57:30ZengMDPI AGMolecules1420-30492012-11-011712140581406610.3390/molecules171214058Norcembranoidal Diterpenes from a Formosan Soft Coral Sinularia sp.Yueh-Hsiung KuoPing-Jyun SungChing-Feng WengChia-Hung LeeShow-Ying YangYung-Chi KuoWen-Hung TwanMei-Chin LuJui-Hsin SuWei-Hsuan YenLi-Chung HuTwo norcembranoidal diterpenes, 5-episinuleptolide acetate (1) and scabrolide D (2), were isolated from a Formosan octocoral identified as Sinularia sp. The structures of norcembranoids 1 and 2 were established by spectroscopic methods and by comparison of the spectral data with those of known analogues and 1 was proven to be a new natural product. Norcembranoid 1 was found to exhibit cytotoxicity toward a panel of tumor cells.http://www.mdpi.com/1420-3049/17/12/14058Sinularianorcembranoidal diterpenecytotoxicity
collection DOAJ
language English
format Article
sources DOAJ
author Yueh-Hsiung Kuo
Ping-Jyun Sung
Ching-Feng Weng
Chia-Hung Lee
Show-Ying Yang
Yung-Chi Kuo
Wen-Hung Twan
Mei-Chin Lu
Jui-Hsin Su
Wei-Hsuan Yen
Li-Chung Hu
spellingShingle Yueh-Hsiung Kuo
Ping-Jyun Sung
Ching-Feng Weng
Chia-Hung Lee
Show-Ying Yang
Yung-Chi Kuo
Wen-Hung Twan
Mei-Chin Lu
Jui-Hsin Su
Wei-Hsuan Yen
Li-Chung Hu
Norcembranoidal Diterpenes from a Formosan Soft Coral Sinularia sp.
Molecules
Sinularia
norcembranoidal diterpene
cytotoxicity
author_facet Yueh-Hsiung Kuo
Ping-Jyun Sung
Ching-Feng Weng
Chia-Hung Lee
Show-Ying Yang
Yung-Chi Kuo
Wen-Hung Twan
Mei-Chin Lu
Jui-Hsin Su
Wei-Hsuan Yen
Li-Chung Hu
author_sort Yueh-Hsiung Kuo
title Norcembranoidal Diterpenes from a Formosan Soft Coral Sinularia sp.
title_short Norcembranoidal Diterpenes from a Formosan Soft Coral Sinularia sp.
title_full Norcembranoidal Diterpenes from a Formosan Soft Coral Sinularia sp.
title_fullStr Norcembranoidal Diterpenes from a Formosan Soft Coral Sinularia sp.
title_full_unstemmed Norcembranoidal Diterpenes from a Formosan Soft Coral Sinularia sp.
title_sort norcembranoidal diterpenes from a formosan soft coral sinularia sp.
publisher MDPI AG
series Molecules
issn 1420-3049
publishDate 2012-11-01
description Two norcembranoidal diterpenes, 5-episinuleptolide acetate (1) and scabrolide D (2), were isolated from a Formosan octocoral identified as Sinularia sp. The structures of norcembranoids 1 and 2 were established by spectroscopic methods and by comparison of the spectral data with those of known analogues and 1 was proven to be a new natural product. Norcembranoid 1 was found to exhibit cytotoxicity toward a panel of tumor cells.
topic Sinularia
norcembranoidal diterpene
cytotoxicity
url http://www.mdpi.com/1420-3049/17/12/14058
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