Chromatin interactome mapping at 139 independent breast cancer risk signals

Chromatin interactome mapping at 139 independent breast cancer risk signals

Abstract Background Genome-wide association studies have identified 196 high confidence independent signals associated with breast cancer susceptibility. Variants within these signals frequently fall in distal regulatory DNA elements that control gene expression. Results We designed a Capture Hi-C a...

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Bibliographic Details
Main Authors: Jonathan Beesley, Haran Sivakumaran, Mahdi Moradi Marjaneh, Luize G. Lima, Kristine M. Hillman, Susanne Kaufmann, Natasha Tuano, Nehal Hussein, Sunyoung Ham, Pamela Mukhopadhyay, Stephen Kazakoff, Jason S. Lee, Kyriaki Michailidou, Daniel R. Barnes, Antonis C. Antoniou, Laura Fachal, Alison M. Dunning, Douglas F. Easton, Nicola Waddell, Joseph Rosenbluh, Andreas Möller, Georgia Chenevix-Trench, Juliet D. French, Stacey L. Edwards
Format: Article
Language:English
Published: BMC 2020-01-01
Series:Genome Biology
Online Access:https://doi.org/10.1186/s13059-019-1877-y

Internet

https://doi.org/10.1186/s13059-019-1877-y

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