G Protein-Coupled Receptors in Cancer

G Protein-Coupled Receptors in Cancer

Despite the fact that G protein-coupled receptors (GPCRs) are the largest signal-conveying receptor family and mediate many physiological processes, their role in tumor biology is underappreciated. Numerous lines of evidence now associate GPCRs and their downstream signaling targets in cancer growth...

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Bibliographic Details
Main Authors: Rachel Bar-Shavit, Myriam Maoz, Arun Kancharla, Jeetendra Kumar Nag, Daniel Agranovich, Sorina Grisaru-Granovsky, Beatrice Uziely
Format: Article
Language:English
Published: MDPI AG 2016-08-01
Series:International Journal of Molecular Sciences
Subjects:
G protein-coupled receptors (GPCRs)
protease
protease-activated receptor
protease-activated receptors (PARs)
PH-domain
oncogenes
cancer
LPA(1-6)
CXCR4
Wnt/β-catenin
Hippo/YAP
Online Access:http://www.mdpi.com/1422-0067/17/8/1320

Internet

http://www.mdpi.com/1422-0067/17/8/1320

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