Hyperactivity, perseveration and increased responding during attentional rule acquisition in the Fragile X mouse model
Attentional deficits and executive function impairments are common to many neurodevelopmental disorders of intellectual disability and autism, including Fragile X syndrome. In the knockout mouse model for Fragile X syndrome, significant changes in synaptic plasticity and connectivity are found in th...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2013-11-01
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Series: | Frontiers in Behavioral Neuroscience |
Subjects: | |
Online Access: | http://journal.frontiersin.org/Journal/10.3389/fnbeh.2013.00172/full |