Hyperactivity, perseveration and increased responding during attentional rule acquisition in the Fragile X mouse model

Attentional deficits and executive function impairments are common to many neurodevelopmental disorders of intellectual disability and autism, including Fragile X syndrome. In the knockout mouse model for Fragile X syndrome, significant changes in synaptic plasticity and connectivity are found in th...

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Bibliographic Details
Main Authors: Ioannis eKramvis, Huibert eMansvelder, Maarten eLoos, Rhiannon eMeredith
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-11-01
Series:Frontiers in Behavioral Neuroscience
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnbeh.2013.00172/full