Tetrastatin, the NC1 domain of the α4(IV) collagen chain: a novel potent anti-tumor matrikine.

Tetrastatin, the NC1 domain of the α4(IV) collagen chain: a novel potent anti-tumor matrikine.

BACKGROUND: NC1 domains from α1, α2, α3 and α6(IV) collagen chains were shown to exert anti-tumor or anti-angiogenic activities, whereas the NC1 domain of the α4(IV) chain did not show such activities so far. METHODOLOGY/PRINCIPAL FINDINGS: We demonstrate in the present paper that the NC1 α4(IV) dom...

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Bibliographic Details
Main Authors: Sylvie Brassart-Pasco, Karine Sénéchal, Jessica Thevenard, Laurent Ramont, Jérome Devy, Ludivine Di Stefano, Aurélie Dupont-Deshorgue, Stéphane Brézillon, Jezabel Feru, Jean-François Jazeron, Marie-Danièle Diebold, Sylvie Ricard-Blum, François-Xavier Maquart, Jean Claude Monboisse
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3335157?pdf=render

Internet

http://europepmc.org/articles/PMC3335157?pdf=render

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