Safety of Intravitreal Zoledronic Acid, an Anti-angiogenic Bisphosphonate, in a Rat Model

Purpose: To determine the safety of intravitreal zoledronic acid (ZA) in the rat eye. Methods: Twenty eyes of 20 pigmented rats were randomized into five groups to receive an intravitreal injection of 8, 4, 2 and 1 micrograms (mcg) of ZA, or balanced salt solution (BSS). One week and one month afte...

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Bibliographic Details
Main Authors: Ramin Nourinia, Hamid Ahmadieh, Mozhgan Rezaei-Kanavi, Nasser Shoeibi, Kiana Kamrava, Saeed Karimi
Format: Article
Language:English
Published: Knowledge E 2014-01-01
Series:Journal of Ophthalmic & Vision Research
Subjects:
Online Access:http://www.jovr.org/article.asp?issn=2008-322X;year=2014;volume=9;issue=1;spage=44;epage=49;aulast=Nourinia