Automated Filling Equipment Allows Increase in the Maximum Dose to Be Filled in the Cyclops<sup>®</sup> High Dose Dry Powder Inhalation Device While Maintaining Dispersibility

Automated Filling Equipment Allows Increase in the Maximum Dose to Be Filled in the Cyclops<sup>®</sup> High Dose Dry Powder Inhalation Device While Maintaining Dispersibility

In recent years there has been increasing interest in the pulmonary delivery of high dose dry powder drugs, such as antibiotics. Drugs in this class need to be dosed in doses far over 2.5 mg, and the use of excipients should therefore be minimized. To our knowledge, the effect of the automatic filli...

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Bibliographic Details
Main Authors: Imco Sibum, Paul Hagedoorn, Carel O. Botterman, Henderik W. Frijlink, Floris Grasmeijer
Format: Article
Language:English
Published: MDPI AG 2020-07-01
Series:Pharmaceutics
Subjects:
high dose pulmonary delivery
dry powder inhaler
automatic filling
vacuum drum filler
inhalation
tuberculosis
Online Access:https://www.mdpi.com/1999-4923/12/7/645

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