Influence of blinding on treatment effect size estimate in randomized controlled trials of oral health interventions
Abstract Background Recent methodologic evidence suggests that lack of blinding in randomized trials can result in under- or overestimation of the treatment effect size. The objective of this study is to quantify the extent of bias associated with blinding in randomized controlled trials of oral hea...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2018-05-01
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Series: | BMC Medical Research Methodology |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s12874-018-0491-0 |