Influence of blinding on treatment effect size estimate in randomized controlled trials of oral health interventions

Abstract Background Recent methodologic evidence suggests that lack of blinding in randomized trials can result in under- or overestimation of the treatment effect size. The objective of this study is to quantify the extent of bias associated with blinding in randomized controlled trials of oral hea...

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Bibliographic Details
Main Authors: Humam Saltaji, Susan Armijo-Olivo, Greta G. Cummings, Maryam Amin, Bruno R. da Costa, Carlos Flores-Mir
Format: Article
Language:English
Published: BMC 2018-05-01
Series:BMC Medical Research Methodology
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12874-018-0491-0