Defective T Memory Cell Differentiation after Varicella Zoster Vaccination in Older Individuals.

Defective T Memory Cell Differentiation after Varicella Zoster Vaccination in Older Individuals.

Vaccination with attenuated live varicella zoster virus (VZV) can prevent zoster reactivation, but protection is incomplete especially in an older population. To decipher the molecular mechanisms underlying variable vaccine responses, T- and B-cell responses to VZV vaccination were examined in indiv...

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Bibliographic Details
Main Authors: Qian Qi, Mary M Cavanagh, Sabine Le Saux, Lisa E Wagar, Sally Mackey, Jinyu Hu, Holden Maecker, Gary E Swan, Mark M Davis, Cornelia L Dekker, Lu Tian, Cornelia M Weyand, Jörg J Goronzy
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-10-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1005892

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https://doi.org/10.1371/journal.ppat.1005892

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