Rifaximin as a Potential Treatment for IgA Nephropathy in a Humanized Mice Model

Rifaximin as a Potential Treatment for IgA Nephropathy in a Humanized Mice Model

IgA Nephropathy (IgAN) is the most common glomerulonephritis worldwide, characterized by the mesangial deposition of abnormally glycosylated IgA1 (Gd-IgA). The production of Gd-IgA occurs in mucose-associated lymphoid tissue (MALT). The microbiota plays a role in MALT modulation. Rifaximin (NORMIX&l...

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Bibliographic Details
Main Authors: Vincenzo Di Leo, Patrick J. Gleeson, Fabio Sallustio, Carine Bounaix, Jennifer Da Silva, Gesualdo Loreto, Sanae Ben Mkaddem, Renato C. Monteiro
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:Journal of Personalized Medicine
Subjects:
IgA Nephropathy
rifaximin
microbiota
α1<sup>KI</sup>-CD89<sup>Tg</sup> mice
Online Access:https://www.mdpi.com/2075-4426/11/4/309

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https://www.mdpi.com/2075-4426/11/4/309

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