Asthma changes at a Pediatric Intensive Care Unit after 10 years: Observational study

Objectives: To describe the change in the management, and outcome of children with acute severe asthma (ASA) admitted to Pediatric Intensive Care Unit (PICU) at tertiary institute, as compared to previously published report in 2003. Methods : This is a retrospective observational study. All consecu...

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Main Authors: Ayman A Al-Eyadhy, Mohamad-Hani Temsah, Ali A. N. Alhaboob, Abdulmalik K Aldubayan, Nasser A Almousa, Abdulrahman M Alsharidah, Mohammed I Alangari, Abdulrahman M Alshaya
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2015-01-01
Series:Annals of Thoracic Medicine
Subjects:
Online Access:http://www.thoracicmedicine.org/article.asp?issn=1817-1737;year=2015;volume=10;issue=4;spage=243;epage=248;aulast=Al-Eyadhy
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spelling doaj-fc5ab41b23ed4734b48d5728f7eb2d792020-11-24T22:44:31ZengWolters Kluwer Medknow PublicationsAnnals of Thoracic Medicine1817-17371998-35572015-01-0110424324810.4103/1817-1737.165302Asthma changes at a Pediatric Intensive Care Unit after 10 years: Observational studyAyman A Al-EyadhyMohamad-Hani TemsahAli A. N. AlhaboobAbdulmalik K AldubayanNasser A AlmousaAbdulrahman M AlsharidahMohammed I AlangariAbdulrahman M AlshayaObjectives: To describe the change in the management, and outcome of children with acute severe asthma (ASA) admitted to Pediatric Intensive Care Unit (PICU) at tertiary institute, as compared to previously published report in 2003. Methods : This is a retrospective observational study. All consecutive pediatric ASA patients who were admitted to PICU during the study period were included. The data were extracted from PICU database and medical records. The Cohort in this study (2013 Cohort) was compared with the Cohort of ASA, which was published in 2003 from the same institution (2003 Cohort). Results: In comparison to previous 2003 Cohort, current Cohort (2013) revealed higher mean age (5.5 vs. 3.6 years; P ≤ 0.001), higher rate of PICU admission (20.3% vs. 3.6%; P ≤ 0.007), less patients who received maintenance inhaled steroids (43.3% vs. 62.4%; P ≤ 0.03), less patients with pH <7.3 (17.9% vs. 42.9%; P ≤ 0.001). There were more patients in 2013 Cohort who received: Inhaled Ipratropium bromide (97% vs. 68%; P ≤ 0.001), intravenous magnesium sulfate (68.2% vs. none), intravenous salbutamol (13.6% vs. 3.6%; P ≤ 0.015), and noninvasive ventilation (NIV) (35.8% vs. none) while no patients were treated with theophylline (none vs. 62.5%). The median length of stay (LOS) was 2 days while mean LOS was half a day longer in the 2013 Cohort. None of our patients required intubation, and there was no mortality. Conclusion: We observed slight shift toward older age, considerably increased the rate of PICU admission, increased utilization of Ipratropium bromide, magnesium sulfate, and NIV as important modalities of treatment.http://www.thoracicmedicine.org/article.asp?issn=1817-1737;year=2015;volume=10;issue=4;spage=243;epage=248;aulast=Al-EyadhyAsthmachildrencritical careepidemiologynoninvasive ventilationpediatricSaudistatus asthmaticus
collection DOAJ
language English
format Article
sources DOAJ
author Ayman A Al-Eyadhy
Mohamad-Hani Temsah
Ali A. N. Alhaboob
Abdulmalik K Aldubayan
Nasser A Almousa
Abdulrahman M Alsharidah
Mohammed I Alangari
Abdulrahman M Alshaya
spellingShingle Ayman A Al-Eyadhy
Mohamad-Hani Temsah
Ali A. N. Alhaboob
Abdulmalik K Aldubayan
Nasser A Almousa
Abdulrahman M Alsharidah
Mohammed I Alangari
Abdulrahman M Alshaya
Asthma changes at a Pediatric Intensive Care Unit after 10 years: Observational study
Annals of Thoracic Medicine
Asthma
children
critical care
epidemiology
noninvasive ventilation
pediatric
Saudi
status asthmaticus
author_facet Ayman A Al-Eyadhy
Mohamad-Hani Temsah
Ali A. N. Alhaboob
Abdulmalik K Aldubayan
Nasser A Almousa
Abdulrahman M Alsharidah
Mohammed I Alangari
Abdulrahman M Alshaya
author_sort Ayman A Al-Eyadhy
title Asthma changes at a Pediatric Intensive Care Unit after 10 years: Observational study
title_short Asthma changes at a Pediatric Intensive Care Unit after 10 years: Observational study
title_full Asthma changes at a Pediatric Intensive Care Unit after 10 years: Observational study
title_fullStr Asthma changes at a Pediatric Intensive Care Unit after 10 years: Observational study
title_full_unstemmed Asthma changes at a Pediatric Intensive Care Unit after 10 years: Observational study
title_sort asthma changes at a pediatric intensive care unit after 10 years: observational study
publisher Wolters Kluwer Medknow Publications
series Annals of Thoracic Medicine
issn 1817-1737
1998-3557
publishDate 2015-01-01
description Objectives: To describe the change in the management, and outcome of children with acute severe asthma (ASA) admitted to Pediatric Intensive Care Unit (PICU) at tertiary institute, as compared to previously published report in 2003. Methods : This is a retrospective observational study. All consecutive pediatric ASA patients who were admitted to PICU during the study period were included. The data were extracted from PICU database and medical records. The Cohort in this study (2013 Cohort) was compared with the Cohort of ASA, which was published in 2003 from the same institution (2003 Cohort). Results: In comparison to previous 2003 Cohort, current Cohort (2013) revealed higher mean age (5.5 vs. 3.6 years; P ≤ 0.001), higher rate of PICU admission (20.3% vs. 3.6%; P ≤ 0.007), less patients who received maintenance inhaled steroids (43.3% vs. 62.4%; P ≤ 0.03), less patients with pH <7.3 (17.9% vs. 42.9%; P ≤ 0.001). There were more patients in 2013 Cohort who received: Inhaled Ipratropium bromide (97% vs. 68%; P ≤ 0.001), intravenous magnesium sulfate (68.2% vs. none), intravenous salbutamol (13.6% vs. 3.6%; P ≤ 0.015), and noninvasive ventilation (NIV) (35.8% vs. none) while no patients were treated with theophylline (none vs. 62.5%). The median length of stay (LOS) was 2 days while mean LOS was half a day longer in the 2013 Cohort. None of our patients required intubation, and there was no mortality. Conclusion: We observed slight shift toward older age, considerably increased the rate of PICU admission, increased utilization of Ipratropium bromide, magnesium sulfate, and NIV as important modalities of treatment.
topic Asthma
children
critical care
epidemiology
noninvasive ventilation
pediatric
Saudi
status asthmaticus
url http://www.thoracicmedicine.org/article.asp?issn=1817-1737;year=2015;volume=10;issue=4;spage=243;epage=248;aulast=Al-Eyadhy
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