Genome-wide association study followed by trans-ancestry meta-analysis identify 17 new risk loci for schizophrenia

Genome-wide association study followed by trans-ancestry meta-analysis identify 17 new risk loci for schizophrenia

Abstract Background Over 200 schizophrenia risk loci have been identified by genome-wide association studies (GWASs). However, the majority of risk loci were identified in populations of European ancestry (EUR), potentially missing important biological insights. It is important to perform 5 GWASs in...

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Bibliographic Details
Main Authors: Jiewei Liu, Shiwu Li, Xiaoyan Li, Wenqiang Li, Yongfeng Yang, Suqin Guo, Luxian Lv, Xiao Xiao, Yong-Gang Yao, Fanglin Guan, Ming Li, Xiong-Jian Luo
Format: Article
Language:English
Published: BMC 2021-08-01
Series:BMC Medicine
Subjects:
Schizophrenia
GWAS
Han Chinese
PRS
TWAS
Meta-analysis
Online Access:https://doi.org/10.1186/s12916-021-02039-9

Internet

https://doi.org/10.1186/s12916-021-02039-9

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