Inflammation and NFκB activation is decreased by hypothermia following global cerebral ischemia

We previously showed that hypothermia attenuates inflammation in focal cerebral ischemia (FCI) by suppressing activating kinases of nuclear factor-kappa B (NFκB). Here we characterize the inflammatory response in global cerebral ischemia (GCI), and the influence of mild hypothermia. Rodents were sub...

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Bibliographic Details
Main Authors: Carla M. Webster, Stephen Kelly, Maya A. Koike, Valerie Y. Chock, Rona G. Giffard, Midori A. Yenari
Format: Article
Language:English
Published: Elsevier 2009-02-01
Series:Neurobiology of Disease
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996108002672