Protein trans-splicing as a protein ligation tool to study protein structure and function

Protein trans-splicing (PTS) exerted by split inteins is a protein ligation reaction which enables overcoming the barriers of conventional heterologous protein production. We provide an overview of the current state-of-the-art in split intein engineering, as well as the achievements of PTS technolog...

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Bibliographic Details
Main Authors: Aranko A. Sesilja, Volkmann Gerrit
Format: Article
Language:English
Published: De Gruyter 2011-06-01
Series:Biomolecular Concepts
Subjects:
Online Access:https://doi.org/10.1515/bmc.2011.014