Cell-type and fetal-sex-specific targets of prenatal alcohol exposure in developing mouse cerebral cortex

Summary: Prenatal alcohol exposure (PAE) results in cerebral cortical dysgenesis. Single-cell RNA sequencing was performed on murine fetal cerebral cortical cells from six timed pregnancies, to decipher persistent cell- and sex-specific effects of an episode of PAE during early neurogenesis. We foun...

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Bibliographic Details
Main Authors: Nihal A. Salem, Amanda H. Mahnke, Kranti Konganti, Andrew E. Hillhouse, Rajesh C. Miranda
Format: Article
Language:English
Published: Elsevier 2021-05-01
Series:iScience
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004221004077