Interleukin-1 as an injury signal mobilizes retinyl esters in hepatic stellate cells through down regulation of lecithin retinol acyltransferase.

Interleukin-1 as an injury signal mobilizes retinyl esters in hepatic stellate cells through down regulation of lecithin retinol acyltransferase.

Retinoids are mostly stored as retinyl esters in hepatic stellate cells (HSCs) through esterification of retinol and fatty acid, catalyzed by lecithin-retinol acyltransferase (LRAT). This study is designated to address how retinyl esters are mobilized in liver injury for tissue repair and wound heal...

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Bibliographic Details
Main Authors: Yujiro Kida, Zanxian Xia, Sujun Zheng, Nicholas M Mordwinkin, Stan G Louie, Song Guo Zheng, Min Feng, Hongbo Shi, Zhongping Duan, Yuan-Ping Han
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3208544?pdf=render

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http://europepmc.org/articles/PMC3208544?pdf=render

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