The GPI anchor signal sequence dictates the folding and functionality of the Als5 adhesin from Candida albicans.

The GPI anchor signal sequence dictates the folding and functionality of the Als5 adhesin from Candida albicans.

BACKGROUND: Proteins destined to be Glycosylphosphatidylinositol (GPI) anchored are translocated into the ER lumen completely before the C-terminal GPI anchor attachment signal sequence (SS) is removed by the GPI-transamidase and replaced by a pre-formed GPI anchor precursor. Does the SS have a role...

Full description

Bibliographic Details
Main Authors: Mohammad Faiz Ahmad, Bhawna Yadav, Pravin Kumar, Amrita Puri, Mohit Mazumder, Anwar Ali, Samudrala Gourinath, Rohini Muthuswami, Sneha Sudha Komath
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3324464?pdf=render

Internet

http://europepmc.org/articles/PMC3324464?pdf=render

Similar Items