Persistent Pharmacokinetic Challenges to Pediatric Drug Development

Persistent Pharmacokinetic Challenges to Pediatric Drug Development

The development of new therapeutic agents for the mitigation of pediatric disorders is largely hindered by the inability for investigators to assess pediatric pharmacokinetics (PK) in healthy patients due to substantial safety concerns. Pediatric patients are a clinical moving target for drug delive...

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Bibliographic Details
Main Authors: Daniel eSage, Christopher eKulczar, Wyatt eRoth, Wanqing eLiu, Gregory Thomas Knipp
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-08-01
Series:Frontiers in Genetics
Subjects:
Developmental Biology
Pediatrics
pharmacokinetics
Ontogeny
formulations
Online Access:http://journal.frontiersin.org/Journal/10.3389/fgene.2014.00281/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fgene.2014.00281/full

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