Mouse SPNS2 functions as a sphingosine-1-phosphate transporter in vascular endothelial cells.

Sphingosine-1-phosphate (S1P), a sphingolipid metabolite that is produced inside the cells, regulates a variety of physiological and pathological responses via S1P receptors (S1P1-5). Signal transduction between cells consists of three steps; the synthesis of signaling molecules, their export to the...

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Bibliographic Details
Main Authors: Yu Hisano, Naoki Kobayashi, Akihito Yamaguchi, Tsuyoshi Nishi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3379171?pdf=render