Mutation of microphthalmia-associated transcription factor (mitf) in zebrafish sensitizes for glomerulopathy

Different glomerular diseases that affect podocyte homeostasis can clinically present as nephrotic syndrome with massive proteinuria, hypoalbuminemia, hyperlipidemia and edema. Up to now, no drugs that specifically target the actin cytoskeleton of podocytes are on the market and model systems for li...

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Bibliographic Details
Main Authors: Janina Müller-Deile, Heiko Schenk, Philipp Niggemann, Patricia Bolaños-Palmieri, Beina Teng, Alysha Higgs, Lynne Staggs, Hermann Haller, Patricia Schroder, Mario Schiffer
Format: Article
Language:English
Published: The Company of Biologists 2019-03-01
Series:Biology Open
Subjects:
PAN
Online Access:http://bio.biologists.org/content/8/3/bio040253