Modulation of T cell function by combination of epitope specific and low dose anticytokine therapy controls autoimmune arthritis.

Modulation of T cell function by combination of epitope specific and low dose anticytokine therapy controls autoimmune arthritis.

Innate and adaptive immunity contribute to the pathogenesis of autoimmune arthritis by generating and maintaining inflammation, which leads to tissue damage. Current biological therapies target innate immunity, eminently by interfering with single pro-inflammatory cytokine pathways. This approach ha...

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Bibliographic Details
Main Authors: Sarah T A Roord, Evelien Zonneveld-Huijssoon, Tho Le, Gisella Puga Yung, Eva Koffeman, Arash Ronaghy, Negar Ghahramani, Paola Lanza, Rosario Billetta, Berent J Prakken, Salvatore Albani
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2006-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC1762388?pdf=render

Internet

http://europepmc.org/articles/PMC1762388?pdf=render

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