Butyrate and Propionate Restore the Cytokine and House Dust Mite Compromised Barrier Function of Human Bronchial Airway Epithelial Cells

Butyrate and Propionate Restore the Cytokine and House Dust Mite Compromised Barrier Function of Human Bronchial Airway Epithelial Cells

Barrier dysfunction of airway epithelium contributes to the development of allergies, airway hyper-responsiveness and immunological respiratory diseases. Short-chain fatty acids (SCFA) enhance and restore the barrier function of the intestinal epithelium. This study investigated whether acetate, pro...

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Bibliographic Details
Main Authors: Levi B. Richards, Meng Li, Gert Folkerts, Paul A.J. Henricks, Johan Garssen, Betty C.A.M. van Esch
Format: Article
Language:English
Published: MDPI AG 2021-12-01
Series:International Journal of Molecular Sciences
Subjects:
short-chain fatty acids
airway epithelial barrier function
ZO-1
MAPK signalling pathways
Online Access:https://www.mdpi.com/1422-0067/22/1/65

Internet

https://www.mdpi.com/1422-0067/22/1/65

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