Acid-base balance in acute ethylene glycol poisoning in rats treated with fomepizole
Introduction. Ethylene glycol (EG) is relatively nontoxic but undergoes a multi-step oxidation to toxic metabolites, aldehydes and acids. The accumulation of organic acids, mainly glycolates, leads to the development of profound, life-threatening metabolic acidosis. A key therapy is an antidotal tre...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Poznan University of Medical Sciences
2014-03-01
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| Series: | Journal of Medical Science |
| Subjects: | |
| Online Access: | https://jms.ump.edu.pl/index.php/JMS/article/view/40 |